Deficient coacervation of two forms of human tropoelastin associated with supravalvular aortic stenosis

Supravalvular aortic stenosis.

The authors describe the case of an inborn supravalvular aortal stenosis in an adult patient who was successfully treated by a plastic operation of the stenotic portion of the ascendent aorta by means of a synthetic patch. At the same time also a plastic operation of an incompetent mitral valve was made.

Supravalvular Aortic Stenosis

In 3 patients obstruction to left ventricular outflow was shown to be due to a localized narrowing of the aortic root at the point of insertion of the aortic leaflets. The site of obstruction was localized by left heart catheterization and selective angiography. The pathologic findings in 2 patients are described and the problem of the surgical management of this unusual form of aortic stenosis...

Supravalvular Aortic Stenosis

BEFORE Denie and Verheugt (1958)' drew attention to the possibility of diagnosing supravalvular aortic stenosis from the characteristics of the pressure tracings across the aortic valve region, there had been only autopsy reports of 17 cases with supravalvular obstruction. Fourteen of these earlier accounts concern bands or membranes stretching across the aortic lumen2-'0 and only three previou...

Supravalvular aortic stenosis

Supravalvular aortic stenosis.

BEFORE Denie and Verheugt (1958)' drew attention to the possibility of diagnosing supravalvular aortic stenosis from the characteristics of the pressure tracings across the aortic valve region, there had been only autopsy reports of 17 cases with supravalvular obstruction. Fourteen of these earlier accounts concern bands or membranes stretching across the aortic lumen2-'0 and only three previou...